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Although the Nrf2 antioxidant pathway is known to offer protective effects, the specific regulatory mechanisms involved in arsenic-induced nephrotoxicity are not yet fully understood [179]

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GHRP-6 and Hexarelin are earlier ghrelin-receptor agonists that act on the same receptor as Ipamorelin but trigger broader endocrine responses, including cortisol, prolactin, and ACTH elevations, which limits their usefulness as clean ghrelin-pathway reference tools

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