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As a result, T cells within tumors exhibit diminished mitochondrial mass, membrane potential, and respiratory capacity, contributing to their functional exhaustion

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Norwood K, Wang RY, Hirschmann-Jax C, Andreeff M , Brenner MK, Goodell MA, Wulf GG

Intussusceptive angiogenesis A less studied process of neo-angiogenesis is intussusception, where transluminal tissue pillars develop within existing vessels and subsequently fuse to remodel the vascular plexus, first described in remodeling of lung capillaries [29, 30]