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Because flavonoids readily cross the placenta, the fetus can be particularly at risk (Skibola and Martyn, 2000)

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Common causes include pernicious anaemia (autoimmune condition), plant-based diets without supplementation, gastrointestinal surgery, and long-term use of metformin or proton pump inhibitors

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While oral supplements play a role, achieving optimal weight management might necessitate more comprehensive approaches