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2009 Jul-Aug;2(3):11929

They needed a delivery system capable of depositing the peptide deep into the follicular infundibulum and retaining it there

Researchers have explored DSIP for possible effects on sleep regulation, stress response, pain signaling, endocrine function, and nervous system activity

Acknowledgements We acknowledge funding from Research Ireland (12/RC/2275_P2), the Irish Research Council (IRCLA/2022/3815), and the Novo Nordisk Foundation (NNF19OC0056845)

Several techniques have been developed to overcome this challenge, including bone marrow stimulation, osteochondral autografting, autologous chondrocyte implantation, and, more recently, mesenchymal stem cell (MSC) implantation [3]

Cai et al., 2020) (Figure 1)