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Their further research showed (127) that GCK could inhibit the abnormal activation and differentiation of T cells in CIA and AIA animal models, and its potential molecular mechanism might be the inhibition of CCL21/CCR7-mediated DC migration and signal transduction between T cells and DC

Knockdown of STAT3 or use of the STAT3 inhibitor W1131 can induce ferroptosis through Fe 2+ accumulation and lipid peroxidation in gastric cancer cells

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