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Science 320 , 16381643 (2008)

Causes, consequences and public health implications of low B-vitamin status in ageing

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Although -glutamyl-peptides per se did not directly protect cells against ferroptosis under cystine starvation, their biosynthesis consumes glutamate, an intracellular amino acid that was previously implied in ferroptosis induction via glutaminolysis 13

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Targeted peptides may permit a quicker return of normal tissue function because they minimize collateral suppression of growth and repair signals