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In detox, moderate doses (e.g., 2,50010,000 IU per day, depending on baseline deficiency) may be used under medical supervision, especially in individuals with documented deficiency

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Summary: Vitamin B12 treatment typically begins producing early haematological responses within 34 days, with neurological symptoms starting to improve within 12 weeks, though complete symptom resolution may require several weeks to months depending on deficiency severity and treatment route

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This shift doesn't "stop" pigment entirely, but it changes the hue of the pigment being produced, which many people find results in a brighter, "glowing" appearance