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In animal research, combined use shows improved results: Quicker formation of granulation tissue and wound closure Decreased edema and inflammation Better tendon-to-bone integration and ligament tensile load Systemic effects on the protection of distant organs, such as the liver and kidney in ischemia-reperfusion

A restrained design often gives cleaner safety data

Johansen PB, Nowak J, Skjaerbaek C, et al

The two molecules work in a continuous redox loop

Frostbite injury led to increased behavioral responses to cold stimuli, as indicated by higher response scores and paw lift frequencies compared to uninjured controls

Animals were housed in polypropylene cages under hygienic and standard environmental conditions (28 C 2 C, humidity 6070%, 12 h light/dark cycle)