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Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice

10.1111/j.1364-3703.2009.00558.x 181 ZhaoJ.WangJ.AnL.DoergeR

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M1 microglia promote the production and release of pro-inflammatory cytokines, exacerbating nerve damage, while M2 microglia promote the release of repairing and phagocytic neurotrophic factors to maintain immune system balance

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4.3 Gluten as a possible epigenetic modifier Whether gluten directly imprints durable epigenetic programs relevant to HT remains unresolved, but several observations justify continued study