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This state is the pinnacle of stability

Overall, these findingsxindicate that Scrophularia radix exerts multi-component and multi-pathway regulatory effects, underscoring its integrative potential in the prevention and treatment of diabetic cerebrovascular complications

Parikh, P

The redox-active sulphydryl group of GSH can protect cells from ROS by directly scavenging free radicals and acting as a cofactor for antioxidant enzymes such as glutathione peroxidases (Gpx1p, Gpx2p and Gpx3p)

The difference between the effects of both QIs on the cell viability ( Figure 2 ) and caspase 3 activation ( Figure 4 ) suggests that upon GSH depletion, the decrease in cell viability is not only apoptosis dependent but also most likely depends other cell death pathways, such as necrosis (Iorga et al., 2017)

Jia and S