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doi:10.1007/s10517-011-1453-2

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Abstract Background Ulcerative colitis (UC) is a chronic inflammatory disorder marked by epithelial barrier disruption and persistent intestinal inflammation

Barrett's esophagus is a condition in which healthy cells in the esophagus turn into unhealthy cells

These variations make it challenging to predict disease course and may lead to delayed recognition of symptom significance (Vercellini et al., 2014)