Patients were stratified into GA and non-GA groups, with propensity score matching to adjust for baseline differences
The main risks are skin irritation with high concentrations and the contamination concerns associated with poorly sourced or improperly prepared formulations
Delivery of copper using BBB permeable delivery agents such as diacetyl-bis (N4-methylthiosemicarbazone) (CuATSM) used to restore copper deficiency in ALS (Hilton et al., 2024), or administration of the endogenously produced neurotrophic copper binding tripeptide Glycyl-L-Histidyl-L-Lysine -copper (GHK-Cu) (Pickart et al., 2017), or else adding PBT2-Cu would be of interest for investigation
Q: What if the regulatory environment reverses again
Food and Drug Administration (FDA) warns that this practice drastically increases the risk of liver failure, as both substances are metabolized in the liver, causing toxic damage when combined
A deficiency in these vitamins can contribute to fatigue