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Observed effects in human trials Reported adverse events across the IV and oral trials included headache, fatigue, dizziness, nasopharyngitis, diarrhea, flatulence, increased appetite, nausea, and back pain

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For weight loss, though, its key advantage is metabolic flexibility : it helps the body switch to burning fat stores and may reduce insulin resistance, attacking one root cause of weight gain

The reasoning: when the tablet dissolves on the tongue, some absorption happens through the oral mucosa (buccal absorption)

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Yes, B12 injections are generally very safe when administered by trained medical professionals