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Notably, no significant difference was observed between animals treated with daily free drugs and those treated weekly with nanoformulations, suggesting similar efficacy with a reduced dosing frequency

Treatment with rapamycin reversed these impairments by downregulating the phosphorylated AKT/mTOR pathway and upregulating BNIP3, AMBRA1, and Parkin expression

Through meticulous observation of patients demeanor, physique, and tongue manifestations, psychological states such as chronic depression, anxiety, or excessive mental strain may exacerbate AMS progression (Zhang et al., 2019)

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Tesoriere L, D'Arpa D, Butera D, et al