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Schisandrin B shows neuroprotective effect in 6-OHDA-induced Parkinsons disease via inhibiting the negative modulation of miR-34a on Nrf2 pathway
They are discussed for overlapping reasons, but they come from different biological concepts, are studied through different mechanisms, and raise different safety and regulatory questions
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Tendon and ligament repair, gastrointestinal mucosal healing, soft tissue recovery, and neuroprotective signaling are all supported by reproducible rodent and in vitro work, while the human evidence remains limited to one unpublished Phase 2 IBD trial and a small number of preliminary studies
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