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Iron deficiency also disrupts Ca 2+ homeostasis: non-selective cation channels in the RBC membranecritical for Ca 2+ entryare upregulated by iron depletion, possibly via ROS-mediated gating

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Subsequent validation through animal experiments, in which mice were gavaged with this bacterial subtype, confirmed its enhanced survival and activity within the gastrointestinal tract (Zepeda-Rivera et al., 2024)

In a typical encapsulation experiment, PLGA nanoparticles exhibited a hydrodynamic diameter of 170 30 nm (z-average, PDI = 0.162) as measured using dynamic light scattering with anionic effective surface charge (20.5 5.3 mV) due to the terminal carboxylate groups on the PLGA polymers