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It contains benzyl alcohol, which has known limitations in certain populations (notably neonates)

Withaferin A (WA), a steroidal lactone obtained from Withania somnifera extract, inhibits neuro-apoptosis, modulates vascular smooth muscle cell (VSMC) migration, and activates PI3K/Akt signaling

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While its a functional disorder without structural damage, BPC-157 may provide symptom relief by: Modulating nitric oxide and serotonin activity Reducing visceral pain and inflammation Normalizing motility through enteric nervous system regulation BPC-157s neural and anti-inflammatory support makes it a candidate for addressing both the gut-brain axis and local irritation in IBS patients

[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Ilic S., Drmic D., Zarkovic K., Kolenc D., Brcic L., Radic B., Djuzel V., Blagaic A.B., Romic Z., Dzidic S., et al