For this reason we believe the most effective plasmid design should place Gpx closest to the promoter, where it has the highest probability of being fully transcribed by RNA polymerase, and GR furthest from the promoter, since high concentrations of GR appear to be less critical given its efficacy
Facile Hydrophobication of Glutathione-Protected Gold Nanoclusters and Encapsulation into Poly(lactide-co-glycolide) Nanocarriers
Garca-Gimnez et al., 2013
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doi: 10.1079/BJN20051577 88