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Rushing produces damaged peptide

Yet, scientists must select a reputable vendor of high-quality compounds, as obtaining pure 5-amino-1MQ is essential for study success

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When gain-of-function LRRK2 mutants are anchored to mitochondria, it phosphorylates and traps Rab10 nearby (Gomez et al., 2019), causing decreased interaction of Rab10 with OPTN (optineurin), which is an autophagy receptor, therefore impairing mitophagy (Wauters et al., 2020)

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