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APOE, primarily synthesized by astrocytes and secreted as HDL-like particles, facilitates lipid trafficking via low-density lipoprotein receptor (LDLR)-mediated uptake

If they dont, they enter into a phase called senescence

183 CX3CR1-deficient mice show a temporary decrease in the number of microglia and a resulting deficiency of synaptic pruning, which may be related to neurodevelopmental and neuropsychiatric disorders

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Total, pro and BDNF measurements by ELISA All serum samples were measured for total BDNF levels using the total BDNF Quantikine ELISA kit(Cat

We first confirmed the screen result in the follow-up experiments and showed that two lines of SLC25A32 CRISPR KO cells proliferated slower than the control, but the growth rate of these KOs were comparable to the control cells in the galactose condition (Fig