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However, more randomized clinical trials are needed for a comprehensive conclusion

Hakimi O, Cameron LC

Limiting alcohol to occasional moderate intake (1-2 drinks maximum, 2-3 times weekly) preserves response

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If there is too much acetaminophen, the liver becomes overwhelmed, and it cannot clear acetaminophens toxic metabolite, which can cause liver damage, says Robert Green, a pharmacist at Johns Hopkins Outpatient Pharmacy