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What the Drug Interaction Databases Say Major drug interaction databases (Lexicomp, Micromedex, Clinical Pharmacology) do not list a GHK-Cu/metformin interaction

Injectable applications demand strict consideration of the patients total systemic copper load, making the compound absolutely contraindicated for individuals suffering from genetic conditions affecting copper metabolism, such as Wilsons disease or Menkes disease

in which dietary GLY and CYS supplementation, targeting age-associated glutathione decline, significantly lowered F 2 -IsoPs (Reference Sekhar, Patel and Guthikonda21)

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Front Genet 3 : 237