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Significant changes suggest degradation has occurred

However, in recent years, numerous studies have suggested that certain subpopulations of senescent cancer cells may regain the ability to proliferate by escaping the senescence process [45, 46]

5 Conclusion In conclusion, the proposed computational AEP and AOP-based models compile and consolidate the mechanistic connections identified to date, while also highlighting knowledge gaps related to joint exposures to radon and tobacco smoke

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