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4,5 Reduced range of motion despite analgesic injection is diagnostic in such instances

10.1038/nature11582

(1996) published the Phase I clinical study of MT-II demonstrating melanotropic activity (PMID 8637402)

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Although these studies have shown the great potential of curcumin in the treatment of UC, more rigorous and in-depth clinical controlled trials are still needed for verification due to the non-standardized dosage forms, dosages, treatment timing, and administration routes in the clinical trials [259, 260]

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