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Molecular simulation studies further confirmed that PI3K is the main target of the two active ingredients, providing theoretical support for further understanding the antidepressant mechanism of CSS

It does not raise cortisol or prolactin levels, which are hormones linked to stress and unwanted side effects

CAS Number : 62568-57-4 Molar Mass : 848.8 g/mol Chemical Formula : C35H48N10O15 IUPAC Name : DL-tryptophyl-DL-alanyl-glycyl-glycyl-DL-alpha-aspartyl-DL-alanyl-DL-seryl-glycyl-DL-glutamic acid Synonyms for DSIP (Delta Sleep-Inducing Peptide): Somnogenic peptide, Delta sleep-inducing peptide, DSIP peptide

Davis et al., 2011) and reduced food reward as measured by conditioned place preference (Zigman et al., 2005

In brief, the protocol consists of the following steps: (1) generation of flexible regions in FOXO4 FH (residues 86-104 and 186-207), the p53 TAD2 peptide, and spin labels, randomization of the flexible regions

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