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Another synthetic strategy involves iron homeostasis modulators (iron chelators), which act by binding free Fe + , thereby blocking the Fenton reaction, reducing hydroxyl radical generation, and preventing the initiation of lipid peroxidation

As clearly seen in this figure, the core-shell nanofibers with drugs are superior to their drug free counterparts in terms of tensile strength (3.4 MPa vs 3 MPa, i.e., 13% increment), elongation (30.4% vs 28.6%, i.e., 6.3% increment), and elastic modulus (0.33 MPa vs 0.25 MPa, i.e., 32% increment)

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