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When asked about the impact of Covid-19, 58% said the pandemic had affected their care, including treatments being stopped or cancelled

Despite these therapies not being initially designed to trigger cellular senescence, it was discovered as early as 1998 that cisplatin could induce cellular senescence in head and neck cancer cells [53]

Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB

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The differentiation of RGC-5 cells with HDAC inhibitors might be due to elimination of neuron gene-specific transcription repressorneuron restrictive silencing factor (NRSF) from NRSE

doi: 10.1073/pnas.1000082107 110 EdelblumKLSharonGSinghGOdenwaldMASailerACaoSet al