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Description

Ca 2+ is a master regulator of eryptosis, mediating the Gardos effect-associated RBC dehydration and reduction of cell volume (cell shrinkage), calpain activation-mediated cytoskeleton remodeling (membrane blebbing), and PS externalization, which are major hallmarks of eryptosis

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B6 is a rate limiting cofactor in the synthesis of several neurotransmitters such as dopamine, serotonin, -aminobutyric acid (GABA), noradrenaline and the hormone melatonin (1)

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