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Reduced oxygenation shows up as paleness, a sallow or washed-out complexion, and slower wound healing

Nature cell biology 2013;15, 978990, doi: Kuilman, T

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For inflammatory bowel disease, mesalamine, corticosteroids, immunomodulators (azathioprine, methotrexate), and biologics (infliximab, adalimumab, vedolizumab, ustekinumab) all have Level 1 evidence from Phase III trials with thousands of patients

This is where the affected tendons attach