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The exact mechanisms by which these cognitive changes are triggered by repeated concussion (rather than physical disruption of neural tissue) remain unclear, though several studies have suggested that neurotoxicity, functional impairment of neuronal synapses, and axonal stabilization by aberrant microtubule-associated protein (MAP) tau may contribute to memory impairment and loss (79, 80) (Figures 1A,B)

The numbers back it up

doi:10.1161/hc3601.093976 Zulli A, Lau E, Wijaya BP, et al

But repeated injections carry real risks: plantar fascia rupture, fat pad atrophy, weakened tendon structure

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