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Possible side effects of IGF-1 LR3 administration can include [1, 14, 15]: Hyperandrogenism Muscle and joint pain Nausea Headache Impaired glucose metabolism and hypoglycemia Fatigue Changes in sexual function Soft tissue swelling Researchers should thoroughly check glucose, cholesterol, and bone density levels before administering IGF-1 LR3 to test subjects

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In the dynamic simulation of GSH_a, the conformation exhibiting a hydrogen bond between N259 and the ligand occurs 100% of the time, while E255 appears over 95% (Table 3)

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PMID: 38 GaoMLiuZZhaoZWangZHuXJiangYet al