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Journal of renal nutrition: the official journal of the Council on Renal Nutrition of the National Kidney Foundation
In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years
The process begins with a thorough consultation to assess your specific needs and determine if this therapy is appropriate for your situation
The circulating figures are research-community conventions
Those with pre-existing conditions such as irritable bowel syndrome (IBS), functional dyspepsia, or gastritis may be more prone to experiencing stomach upset from supplements generally, including B12 preparations
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