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The authors conclude that the findings indicate that the Rhodiola rosea extracts and salidroside commonly induce hormetic dose responses within a broad range of biological models and cell types and across a wide range of endpoints, with particular emphasis on longevity and neuroprotective endpoints [269]

Owing to their distinct biochemical mechanisms that suppress lipid peroxidation and reduce ROS production, these compounds have been investigated in clinical studies to assess the therapeutic value of their antioxidant properties (Table 1)

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