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To test whether the relationship between age and side effects varied across prescription types, age prescription type interaction terms were included in the ANCOVA models for each side effect

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53 Although they have been classified as endocrine disruptors (binding to ER at lower levels compared to 17-estradiol), this is a very narrow view, and these compounds are coming to the forefront as agonist-antagonist SERMs that are especially suited for MHT

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