Glutathione has been shown beneficial for protecting cells and tissues from damage by heavy metal toxicity and other environmental toxins, breaking them down into less harmful compounds and preparing them for excretion
This degree of metal-sensing promiscuity across a collection of closely related ZntRs in a cell is not only anticipated but may well be beneficial, since it is well documented that the P 1B-2 ATPase, ZntA, can efficiently transport a range of divalent soft transition metal ions, including Zn II , Cd II , Pb II and Hg II by adopting a range of coordination geometries in the transmembrane metal binding site (Section 5.3.1)
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We acknowledge Bernhard Hube (Microbial Pathogenicity Mechanisms, Leibniz-HKI) for fruitful discussions and providing access to deletion mutants
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How do antioxidants support electron flow
