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Porphyromonas gingivalis exacerbates experimental autoimmune encephalomyelitis by driving Th1 differentiation via ZAP70/NF-B signaling

In breast cancer, enhanced glycolytic activity regulated by PGK1 contributes to the modulation of the TME by regulating the expression of immune suppressive factors such as PD-L1 and CTLA4 [112]

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One study enrolled over 17,000 overweight or obese adults without diabetes