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With a few drugs, such as phenylbutazone, ethanol, deracoxib, and phenytoin, or if very large doses of a drug are given, the drug concentrations achieved are much greater than K m and the rate equation is as follows: The enzymes are saturated by the high free drug concentrations, and the rate of metabolism remains constant over time

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Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression

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There is no problem for them to drive after the injection