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Ferroptosis plays a crucial role in OA by contributing to chondrocyte death, cartilage degradation, and joint inflammation

HMGB1 acts by binding to various receptors, including RAGE and TLR2, TLR4, and TLR9 [254,255]

Networks of WRKY transcription factors in defense signaling

Novo Nordisk Patients Seeking Upgrade# Recommendation : CagriSema Reason : Patients already on semaglutide (Wegovy) who need greater weight loss can potentially upgrade to CagriSema within the Novo Nordisk ecosystem once approved, leveraging the same GLP-1 component plus added amylin agonism