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Central sensitization reflects altered neural signaling, not ongoing tissue damage

IL-10, interleukin 10

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Psychopharmacology (Berl)

Neurological disorders In conditions like Parkinsons and Alzheimers diseases, disruptions in cellular Ca 2+ regulating systems in the plasma membrane, ER, and mitochondria can manifest in synaptic dysfunction, decreased plasticity, and neuronal degeneration [286,287,288]

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