A doctor may choose injections over oral supplementation to limit any barriers to absorption
Formulation alternatives may provide relief: Different tablet formulations with alternative inactive ingredients may be better tolerated Liquid preparations can be easier to tolerate and allow flexible dosing Intramuscular injections completely avoid the gastrointestinal tract and are particularly useful for those with absorption issues (such as pernicious anaemia or malabsorption) or persistent oral intolerance Review inactive ingredients: Examine the supplement label for potential irritants or allergens
For about an hour following your treatment, you could feel a dull soreness where you had the injections
Who Is Most at Risk for B12 Deficiency
23 Supplementation of 1 mg daily is recommended for patients with specific risk factors (e.g., bariatric/gastric surgery patients, those with severe malnutrition, chronic alcohol use, chronic hemolytic anemia and conditions with high cell turnover, and use of antimetabolite medications such as methotrexate)
(4) Research has demonstrated that NNMT inhibition results in increased intracellular nicotinamide and SAM levels