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In a mouse model, hydrogen-rich water was reported to reduce intestinal inflammation by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression (60)

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Effect of prophylactic MK4 treatment (200 mg/kg, i.p., 24 h and 1 h before IRI) on liver ischemia-reperfusion injury (IRI) in C57BL/6 mice

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In the FSP1/CoQ10/NAD(P)H axis, FSP1 reduces CoQ10 to generate the antioxidant CoQH2 independently of GPX4, inhibits lipid peroxidation [81], and cooperates with vitamin K metabolism to protect cells [82]