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This allows selenium to build up and cause damage to the gut and other tissues because the body cannot easily store it

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Despite this gap in knowledge, a plausible hypothesis could be formulated that either treatment with exogenous melatonin or interventions aimed at restoring endogenous melatonin secretion might offer potential in mitigating neurodegenerative processes induced by circadian disruption

Delgado G, Schatz A, Nichols S, Appelbaum M, Trauner D (2005) Behavioral profiles of children with infantile nephropathic cystinosis

However, this benefit is largely anecdotal and varies from person to person

Participants were then randomized to 3 (n = 243) or 6 (n = 215) months for MRS follow-up