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The human body makes over 7,000 natural peptides vital for biological functions

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Moreover, it carries a higher risk of leak compared to fundoplication alone (2.7% vs

The Ang IV analogue peptide 4 and the Nle-Ang IV analogue 5 provide examples comprising two basic amino groups accessible for protonation in the N-terminal of the peptides and flanking hydrophobic 2-isopropyl and n-butyl side chains, respectively (Figure 2) (Sardinia et al., 1994)