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In hippocampal neuron cultures, Dihexa was reported to induce spinogenesis and synaptogenesis at picomolar concentrations the basis for the widely-cited seven orders of magnitude more potent than BDNF potency figure
Copper(II) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3 inhibition due to intracellular delivery of copper
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By ensuring bile acids are properly conjugated with taurine, the formula promotes smooth bile flow, preventing toxic bile from backing up into the liver (cholestasis) and ensuring that fat-soluble toxins can be effectively escorted out of the body via the gastrointestinal tract
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doi: 10.1126/science.1241165 90 SpaggiariG.BriganteG.De VincentisS.CattiniU.RoliL.De SantisM
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