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Cloudiness that persists after five minutes, visible particulates that do not dissolve, or a strong chemical smell on opening are all physical red flags

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doi: 10.1159/000264816 104 LeopoldJAWalkerJScribnerAWVoetschBZhangYYLoscalzoAJet al

By consequence, this could affect composite restoration sealing ability that leads to high degree of microleakage at the tooth-restoration interface

Vitamin B12 injections are often used for this condition because they get B12 into the blood without going through the digestive system