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This epithelial disruption was linked to elevated serum LPS, confirming increased intestinal permeability and microbial translocation

All imaging data are representative of at least three randomly selected fields

Converging data from several sources suggest, however, that IC/BPS can be conceptualized as a bladder pain disorder that is often associated with voiding symptomatology and other systemic chronic pain disorders

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There was clear increase in bound purified GST-GFP protein (p = 0.00002

This technique measures key kinetic parameters such as the association rate (k_on), dissociation rate (k_off), and equilibrium dissociation constant (K_D) across a range of pH buffers (e.g., from pH 7.4 to 5.5)