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One primary challenge when dealing with compromised skin barriers is the decreased ability of the skin to function as a protective barrier, which is seen in patients with dermatological diseases such as psoriasis, eczema, or burns [345]

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6f and 7c) and increased HMGB-1 expression (Figs

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These cells achieve metabolic homeostasis by regulating the dynamics of nutrients present in the microenvironment, and the ability of cancer cells to utilize them to produce energy and to synthesize macromolecules