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Overcoming barriers for siRNA therapeutics: from bench to bedside

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These pathways include the regulation of the tricarboxylic acid (TCA) cycle, aerobic glycolysis and fatty acid (FA) synthesis, which are crucial for tumour cell survival and proliferation (30,31) and also affect the stromal and immune cell components of the tumour microenvironment (32)

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[Abstract]2024 Jan 5:461:132570

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the resulting working concentration (mg/ml) and the number of units on the scale are determined by the batch COA

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