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Identify gaps in the literature and ongoing research directions Key gaps include a lack of large, controlled clinical trials, unclear optimal dosing and delivery for reproductive targets, limited long-term safety data for systemic use, and few mechanistic human studies linking molecular changes to fertility outcomes
However, it is important to note that while the effects of HCQ and CQ on TLR signaling are well-documented, they are not believed to be the sole mechanisms of these drugs
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Pharmacol Res 2024;200:107076
Short Acting Beat-2 Agonist (SABA) The generic names for most beta-2 agonists end in (albute ro l , formote rol , salmete rol ) rol Figure 1: Structures of commonly used Beta-2 Agonists, albuterol, a Short-Acting Beta 2 Agonist (SABA) and two Long-Acting Beta 2 Agonists (LABAs) formoterol and salmeterol