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At the cellular level, 5-Amino-1MQ promotes differentiation and metabolic reprogramming of precursor cells while being well-tolerated in repeated dosing studies 4

The project co-led by Timothy Marlowe, PhD, associate professor in the Department of Internal Medicine , the U of A Cancer Center and the College of Pharmacy, Michael Fallon, MD, FACP , executive director for Clinical Research and chair of the Department of Internal Medicine, and Hyo Jin Park, PhD, assistant research scientist in the Department of Internal Medicine targets the connection between focal adhesion kinase (FAK) and paxillin, two proteins that become hyperactive during fibrosis and fuel the buildup of scar tissue in the liver